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- > Dogs: Atopic dermatitis in dogs
Atopic dermatitis in dogs (AD) – effective biological treatment
Introduction
Atopic dermatitis (AD) in dogs is a chronic inflammatory skin disease of immunological origin, characterised by itching, redness and frequent secondary infections. It occurs mainly in young and middle-aged dogs, and breeds predisposed to it include Labradors, French Bulldogs, West Highland White Terriers and German Shepherds.
Symptoms of atopic dermatitis:
- chronic itching and scratching of the dog,
- redness and flaking of the skin,
- localised hair loss, abrasions and thickening of the skin,
- secondary bacterial and fungal infections.
Standard treatment
Current treatment methods include the use of steroid anti-inflammatory drugs (glucocorticosteroids, cyclosporine), antibiotics and antifungal preparations, as well as specialised hypoallergenic diets. This treatment helps to alleviate symptoms, but often does not provide lasting improvement and requires long-term use.
Modern biological therapies
Mesenchymal stem cells (MSCs)
MSCs have strong immunomodulatory and anti-inflammatory effects. When administered subcutaneously to affected areas, they reduce inflammation, alleviate itching and support skin regeneration. Clinical trials and veterinary proactivity have shown a significant improvement in the quality of life of dogs suffering from AD.
👉 Check out how mesenchymal stem cells work
PRP – platelet-rich plasma
PRP provides growth factors that promote healing and improve microcirculation in the skin. It can be used as a supportive therapy in patients with chronic dermatological conditions.
Therapy IL-1
In cases of severe AD, where recurrent inflammation predominates, IL-1 therapy helps to reduce the severity of the immune response and alleviate symptoms.
👉 Learn more about IL-1 pain therapy and treatment
Approach depending on the stage of the disease
- Stage 1 – mild symptoms: PRP to support healing and improve skin condition.
- Stage 2 – chronic AD: MSC to modulate the immune system and reduce symptoms.
- Stage 3 – severe and resistant cases: IL-1 in combination with supportive treatment.
Summary
Atopic dermatitis in dogs is a difficult and chronic disease that requires a modern therapeutic approach. Biological therapies – MSC, PRP and IL-1 – offer a real chance to improve patients' quality of life, reduce the need for steroid medication and limit the number of relapses.
FAQ
Atopic dermatitis is chronic, but modern biological therapies can significantly reduce symptoms and improve your dog's quality of life. Inflammation on the skin often disappears within a few weeks of local MSC administration.
Yes – autologous MSCs are used, i.e. cells taken from the patient, which minimises the risk of complications.
Usually several to several months, depending on the severity of the disease and the dog's lifestyle.
Yes – PRP supports skin healing, and MSCs modulate the immune response. The combination produces synergistic effects.
